Koken Collagen microspheres

The atelocollagen microspheres (KKN-MIC-00) is prepared from bovine dermal Type I atelocollagen which provides a 3D matrix similar an in vivo environment for cell culture This product has been successfully used as microcarrier beads for culturing fibroblasts, epithelial cells and osteoblasts, and has proven effective for the long-term maintenance of cell cultures.

The atelocollagen microspheres (KKN-MIC-00) are 200-400 µn;m in diameter. Supplied in 15 mL volume, there are about 2 × 10⁵ microspheres per mL (approx. 3 million particles total).

Product Name

Collagen (Atelocollagen) Microspheres (15 mL)

Catalog Number

KKN-MIC-00

Size

15 mL

Sphere Dimensions

100-400 µm microsphere diameter
approx. 3800 cm² / bottle surface area
approx. 3 × 10⁶ microspheres per bottle

Storage and Stability

Store at 4 °C (do not freeze)

Sterility

Sterile

Notice To Purchaser

REPROCELL is a licensed global distributor of KOKEN’s collagen-derived products everywhere, except for Japan.

Concentration

Approximately 3 million microspheres per 15 mL

Manufacturer

Koken Co., Ltd. (Japan)

• AteloCell Data Sheet

1. Seto I, et al. Mandibular reconstruction using a combination graft of rhBMP-2 with bone marrow cells expanded in vitro. (2006) Plast Reconstr Surg. 117(3):902-908.
2. Kanematsu A, et al. Type I collagen can function as a reservoir of basic fibroblast growth factor. (2004) J Control Release. 99(2):281-292.
3. Konya E, et al. The role of osteopontin on calcium oxalate crystal formation. (2003) Eur Urol. 43(5):564-571.
4. Overstreet M, et al. Collagen microcarrier spinner culture promotes osteoblast proliferation and synthesis of matrix proteins. (2003) In Vitro Cell Dev Biol Anim. 39(5-6):228-234.
5. Frondoza C, et al. Human chondrocytes proliferate and produce matrix components in microcarrier suspension culture. (1996) Biomaterials. 17(9):879-888.