iMatrix-332's features make it an ideal matrix for some cell culture applications:
iMatrix-332is a highly purified and refined product of human recombinant laminin-332 (E8 fragment) expressed by CHO-S cells. Laminin 332 supports cells in the epithelial basement membranes, lining the surfaces of the body such as the skin, hair follicles, oral cavity, gastrointestinal and urinary tracts, lungs, and different glands. The association of cells with laminin 332 occurs through α3β1 integrin in focal adhesions and α6β4 in stable anchoring contacts, which contain an assembly of hemidesmosome proteins.
Laminin-332 is an important component of the "skin basement membrane" that exists between the epithelium and dermis of the skin, and is also expressed in human retinal pigment epithelium (RPE) and hair follicle cells.
Product Name
iMatrix-332Cell Culture Substrate
Catalog Number
NP892-031
NP892-032
Size
Molecular Weight
150 kDa
Purity
>95% pure
Formulation
Purified Laminin-332 E8 proteolytic fragment
Storage and Stability
Store at 4 °C and protect from light exposure. Stable for 2 years from manufacturing date.
Quality Control
Activity: Kd for integrin binding
Sterility
Sterile
Notice To Purchaser
REPROCELL is a licensed distributor of Matrixome cell culture substrates to the global market.
Recommended Usage
iMatrix-332 is suitable for use as a substrate for culture of various cell types.
Concentration
500 µg/mL
Source
CHO-S cell expression
Manufacturer
Matrixome Corporation (Japan)
