{"title":"Growth Factors","description":null,"products":[{"product_id":"stemfactor-fgf-basic-human-recombinant","title":"Stemfactor FGF-basic, Human Recombinant","description":"\u003ch2\u003eFibroblast Growth Factor-basic\u003c\/h2\u003e\n\u003cp\u003eFibroblast Growth Factor-basic (bFGF), also known as FGF-2, is a heparin-binding member of the FGF superfamily of molecules. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues by promoting cellular proliferation and differentiation. Additionally, bFGF is a critical component of embryonic stem cell culture medium, allowing cells to remain in an undifferentiated state in serum-free medium\u003csup\u003e1,2\u003c\/sup\u003e. Stemfactor bFGF is an approximately 17 kDa protein consisting of 155 amino acid residues.\u003cbr\u003e\u003c\/p\u003e","brand":"Stemgent","offers":[{"title":"50 μg","offer_id":45980762865850,"sku":"03-0002","price":185.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0764\/3119\/6346\/files\/stemfactor-fgf-basic-human-recombinant-p203-162_medium_dbfcfa0d-2f5c-4f10-9927-2a8bb4f0e990.jpg?v=1781100653"},{"product_id":"stemfactor-activin-a-human-recombinant","title":"Stemfactor Activin A, Human Recombinant","description":"\u003cp\u003eStemfactor Activin A is a crystallography-grade preparation providing the highest purity available. Activin A is bimodal in action, having been shown to maintain pluripotency of stem cells and promote differentiation\u003csup\u003e1,2,3,4\u003c\/sup\u003e. Mature recombinant human Activin A is a ~25 kDa disulfide-linked homodimer of two 116 amino acid residue βA subunits.\u003c\/p\u003e","brand":"Stemgent","offers":[{"title":"5 μg","offer_id":45980762570938,"sku":"03-0001","price":216.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0764\/3119\/6346\/files\/stemfactor-activin-a-human-recombinant-p202-161_medium_f636f5e3-392f-4582-a8ee-38527698bd3d.png?v=1781100649"},{"product_id":"stemfactor-bmp-4-human-recombinant","title":"Stemfactor BMP-4, Human Recombinant","description":"\u003ch2\u003eBone Morphogenetic Protein 4\u003c\/h2\u003e\n\u003cp\u003eBone Morphogenetic Protein 4 (BMP-4) is a polypeptide belonging to the TGFβ protein superfamily. BMP-4 is involved in bone and cartilage development; more specifically, in tooth and limb development and fracture repair\u003csup\u003e1\u003c\/sup\u003e. In human embryonic development, BMP-4 is a critical signaling molecule required for the early differentiation of the embryo and establishment of a dorsal-ventral axis\u003csup\u003e2,3\u003c\/sup\u003e. BMP-4 plays an important role in the differentiation of overlying ectodermal tissue. Inhibition of the BMP-4 signal causes the ectoderm to differentiate into the neural plate. In cultured stem cells, BMP-4 plays a distinct role in mouse and human embryonic stem (ES) cells. BMP-4 supports LIF as a positive factor for mouse ES cell self-renewal\u003csup\u003e4\u003c\/sup\u003e. In contrast, BMP-4 induces extra-embryonic trophoblast differentiation in human pluripotent stem cells\u003csup\u003e5\u003c\/sup\u003e. Stemfactor BMP-4 is a recombinant protein expressed and purified from human 293 cells as a glycosylated homodimer with a molecular mass of 34 kDa.\u003c\/p\u003e","brand":"Stemgent","offers":[{"title":"10 μg","offer_id":45980762603706,"sku":"03-0007","price":297.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0764\/3119\/6346\/files\/stemfactor-bmp-4-human-recombinant-p205-164_medium_4dcf4385-43ea-4159-8b10-90a84275de36.jpg?v=1781100650"},{"product_id":"stemfactor-lif-human-recombinant","title":"Stemfactor LIF, Human Recombinant","description":"\u003ch2\u003eRecombinant Human LIF\u003c\/h2\u003e\n\u003cp\u003eRecombinant Human LIF is a lymphoid factor that promotes long-term maintenance of the pluripotency of embryonic stem cells by suppressing spontaneous differentiation\u003csup\u003e1,2\u003c\/sup\u003e. Leukemia Inhibitory Factor (LIF) has additional functions such as cholinergic neuron differentiation, bone and fat metabolism, mitogenesis of certain factor-dependent cell lines, and promotion of megakaryocyte production in vivo\u003csup\u003e3\u003c\/sup\u003e. Human LIF is an approximately 20 kDa protein containing 202 amino acid residues and is active on both human and mouse cells.\u003c\/p\u003e","brand":"Stemgent","offers":[{"title":"1 mL (10 μg\/mL)","offer_id":45980763127994,"sku":"03-0016","price":307.0,"currency_code":"USD","in_stock":true},{"title":"1 mL (100 μg\/mL)","offer_id":46329943392442,"sku":"03-0016-100","price":1372.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0764\/3119\/6346\/files\/stemfactor-lif-human-recombinant-p208-168_medium_a69151f3-983b-46cd-88ba-4d59e7ba87df.jpg?v=1781100654"},{"product_id":"stemfactor-lif-mouse-recombinant","title":"Stemfactor LIF, Mouse Recombinant","description":"\u003cp\u003eMouse LIF is a lymphoid factor that promotes long-term maintenance of the pluripotency of mouse embryonic stem cells by suppressing spontaneous differentiation\u003csup\u003e1,2\u003c\/sup\u003e. Leukemia Inhibitory Factor (LIF) has additional functions such as cholinergic neuron differentiation, bone and fat metabolism, mitogenesis of certain factor-dependent cell lines, and promotion of megakaryocyte production \u003cem\u003ein vivo\u003c\/em\u003e. Mouse LIF is an approximately 20 kDa protein containing 202 amino acid residues.\u003c\/p\u003e","brand":"Stemgent","offers":[{"title":"1 ml (10 μg\/mL)","offer_id":45980763160762,"sku":"03-0011","price":292.0,"currency_code":"USD","in_stock":true},{"title":"1 ml (100 μg\/mL)","offer_id":46329943228602,"sku":"03-0011-100","price":1161.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0764\/3119\/6346\/files\/stemfactor-lif-mouse-recombinant-p207-167_medium_2b27ccac-e719-4970-8870-211b43bc33d9.jpg?v=1781100655"}],"url":"https:\/\/store.reprocell.com\/collections\/growth-factors.oembed","provider":"Reprocell","version":"1.0","type":"link"}