{"product_id":"ci-haelvi-immortalized-human-alveolar-epithelial-cells","title":"CI-hAELVi Immortalized Human Alveolar Epithelial Cells","description":"\u003ch2\u003eImmortalized Human Alveolar Epithelial Cells\u003c\/h2\u003e\n\u003cp\u003eCI-hAELVi cells are immortalized human alveolar epithelial cells. Alveolar epithelial cells play a crucial role in the respiratory system by lining the alveoli, tiny air sacs within the lungs where gas exchange occurs. CI-hAELVis have been extensively used to model the air-blood barrier in vitro.\u003c\/p\u003e\n\u003cp\u003eWhile the cells do show an AT-1 phenotype (expression of Caveolin, no surfactant secretion) in standard culture conditions, they adopt certain AT-2 characteristics in extended ALI culture conditions, including secretion of surfactants and formation of microvilli and lamellar structures.\u003c\/p\u003e\n\u003cp\u003eThere is a newer and improved alveolar cell line available, \u003ca href=\"https:\/\/store.reprocell.com\/products\/ci-huarlo-immortalized-human-alveolar-epithelial-cells\"\u003eCI-huArlo\u003c\/a\u003e, which is a direct derivative of CI-hAELVi.\u003c\/p\u003e\n\u003cp\u003eThis CI-hAELVi cell line is the result of a collaboration between HIPS, Saarbrücken (Germany), HZI, Braunschweig (Germany), and inscreenex.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCharacteristics\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTEER of \u0026gt;1500 Ω\/sqcm in Liquid-Liquid-Interface culture\u003c\/li\u003e\n\u003cli\u003eTEER of \u0026gt;2000Ω\/sqcm in Air-Liquid-Interface culture\u003c\/li\u003e\n\u003cli\u003eTight junctions (ZO1, Occludin)\u003c\/li\u003e\n\u003cli\u003eSusceptible to SARS-CoV-2 infection\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCulture Conditions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCulture Medium: huAEC Medium Kit for Alveolar Cells (Cat. No. \u003ca href=\"http:\/\/store.reprocell.com\/products\/huaec-medium-kit-for-alveolar-cells\"\u003eINS-ME-1013\u003c\/a\u003e)\u003c\/li\u003e\n\u003cli\u003eCulture Matrix: Coating Solution  (Cat. No. \u003ca href=\"https:\/\/store.reprocell.com\/products\/coating-solution\"\u003eINS-SU-1026-100ml\u003c\/a\u003e)\u003c\/li\u003e\n\u003cli\u003eCryopreservation Medium: Freezing Solution for Immortalized Cell Lines (Cat. No.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/store.reprocell.com\/products\/freezing-medium-for-immortalized-cell-lines\"\u003eINS-SU-1027\u003c\/a\u003e\u003ca href=\"https:\/\/www.reprocell.com\/product-catalog\/immortalized-cell-lines-and-related-reagents\/freezing-medium-for-immortalized-cell-lines\" rel=\"noopener\"\u003e\u003c\/a\u003e)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eBuying and Ordering the Cells\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eA license for Academic Researchers is also available.  Please \u003ca href=\"https:\/\/store.reprocell.com\/pages\/contact\"\u003econtact us \u003c\/a\u003efor more information\u003c\/p\u003e","brand":"inscreenex","offers":[{"title":"1 vial (500K cells)","offer_id":50648970297530,"sku":"INS-CI-1015","price":9430.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0764\/3119\/6346\/files\/inscreenex-cells-cryovials-2-1024x1024.webp?v=1791203416","url":"https:\/\/store.reprocell.com\/products\/ci-haelvi-immortalized-human-alveolar-epithelial-cells","provider":"Reprocell","version":"1.0","type":"link"}