{"product_id":"imatrix-211-cardiac-and-myoblast-cell-culture-substrate","title":"iMatrix-211 Cardiac and Myoblast Cell Culture Substrate","description":"\u003ch2\u003e\u003cspan\u003e Xeno-free, recombinant Laminin-221 E8 Fragment expressed in CHO-S cells\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eiMatrix-221 is a highly purified and refined product of human recombinant laminin-221 (E8 fragment) expressed by CHO-S cells. Laminin-221 is found predominantly in the basal lamina of striated muscle tissues. Expression deficiencies are implicated in muscular dystrophy and cardiomyopathies.\u003csup\u003e1\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eiMatrix-221's features make it an ideal matrix for some cell culture applications:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eXeno-free formulation \/ CHO-S cell bioproduction\u003c\/li\u003e\n\u003cli\u003eEasy to use (liquid format)\u003c\/li\u003e\n\u003cli\u003eE8 fragments retain integrin binding specificity and capacity, and display higher potency than natural Laminin-221\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eLaminins of the α-2 type are also a predominant form found in the human adult heart tissue.\u003c\/span\u003e\u003csup\u003e2\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eCultivation of iPSC-derived cardiomyocytes on iMatrix-221 has been demonstrated to maintain strong contractility in attached monolayer culture.\u003c\/span\u003e\u003csup\u003e3\u003c\/sup\u003e\u003c\/p\u003e","brand":"Matrixome","offers":[{"title":"175 μg × 2 tubes","offer_id":50533225627834,"sku":"NP892-061","price":509.0,"currency_code":"USD","in_stock":true},{"title":"175 μg × 6 tubes","offer_id":50533225660602,"sku":"NP892-062","price":1418.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0764\/3119\/6346\/files\/iMatrix-211_1.png?v=1790348388","url":"https:\/\/store.reprocell.com\/products\/imatrix-211-cardiac-and-myoblast-cell-culture-substrate","provider":"Reprocell","version":"1.0","type":"link"}