iMatrix 511-SILK Stem Cell Culture Substrate
| QTY | Cat # | Size | Unit Price |
|---|---|---|---|
|
|
NP892-021 | 6 vials | $487.00 |
* Prices listed are in USD. Taxes, shipping & handling not included. Contact us for bulk pricing.
Overview
Recombinant Laminin-511 E8-Fragments, expressed in Silkworm
iMatrix-511 SILK is a highly purified and refined laminin-511 E8 fragments, produced in Silkworms.
iMatrix-511 SILK features make it an ideal matrix for pluripotent stem cell culture:
- Promotes greater stem cell adhesion than all other matrix proteins that have been tested
- Easy to use (liquid format)
- E8 fragments retain integrin binding specificity and capacity, and display higher potency than natural Laminin-511
- Equivalent performance, but lower cost than the legacy iMatrix-511 product.
Laminin is localized to the basement membrane and plays a key role in cell adhesion and proliferation. Laminin-511 (α5, β1 laminin) binds to integrin α6β1 to promote cell signaling. Laminin-511 provides an ideal matrix for the proliferation of a wide variety of cell types, including stem and iPS cells.
iMatrix-511 SILK is functionally equivalent to iMatrix-511 (Cat. No. NP892-011). The only difference is the expression system used for bioproduction. The iMatrix-511 SILK product is produced in recombinant silkworm cocoons, while iMatrix-511 is produced in CHO-S cells. Both are E8 fragments that have been purified using the same processes.