{"product_id":"stemolecule-dapt","title":"Stemolecule DAPT","description":"\u003cp\u003eStemolecule DAPT (also known as GSI-IX or LY-374973), a cell-permeable dipeptide, inhibits γ-secretase and indirectly inhibits Notch, a γ-secretase substrate 1 . Since the Notch pathway is involved in the development of both the nervous system and pancreas, DAPT may be useful in modulating Notch activity in embryonic stem cell differentiation studies 2 . DAPT has been shown to dose-dependently decrease amyloidβ levels via inhibition of γ-secretase in both plasma and cerebral spinal fluid 3 . Since amyloid β containing senile plaques are characteristic in Alzheimer's disease, DAPT may be useful in studies evaluating potential treatments for that disease.\u003c\/p\u003e","brand":"Stemgent","offers":[{"title":"5 mg","offer_id":45980764995770,"sku":"04-0041","price":199.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0764\/3119\/6346\/files\/stemolecule-dapt-p240-59_medium_ffef63b9-7252-4d0f-850a-0ca4e8764953.png?v=1781100700","url":"https:\/\/store.reprocell.com\/products\/stemolecule-dapt","provider":"Reprocell","version":"1.0","type":"link"}