Stemgent
Stemolecule PD0325901
| QTY | Cat # | Size | Unit Price |
|---|---|---|---|
|
|
04-0006 | 2 mg | $276.00 |
|
|
04-0006-10 | 10 mg | $1,081.00 |
|
|
04-0006-02 | 2mg (10mM) | $324.00 |
* Prices listed are in USD. Taxes, shipping & handling not included. Contact us for bulk pricing.
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Overview
PD0325901 is a small molecule targeting mitogen-activated protein kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. PD0325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation 1,2 . Along with the ALK5 inhibitor SB431542, PD0325901 has also been shown to increase the efficiency of reprogramming human primary fibroblasts into induced pluripotent stem (iPS) cells 3 . Also available as a 10 mM stock solution in DMSO (Cat. No. 04-0006-02)