Stemolecule Thiazovivin
Stemgent

Stemolecule Thiazovivin

QTY Cat # Size Unit Price
04-0017 1 mg $285.00

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Overview

Thiazovivin is a selective, cell permeable small molecule that directly targets Rho-associated kinase (ROCK) 1 . In addition, Thiazovivin protects human embryonic stem cells (hESCs) in the absence of ECM by regulating E-cadherin mediated cell-cell interaction 1 . This observation suggests that Thiazovivin promotes cell survival. In other studies Thiazovivin, in combination with inhibitors of the TGFβ receptor and MEK pathway, has shown to improve reprogramming efficiency by more than 200-fold 2 .

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