Stemgent
Stemolecule Wnt Inhibitor IWP-4
| QTY | Cat # | Size | Unit Price |
|---|---|---|---|
|
|
04-0036 | 2 mg | $135.00 |
|
|
04-0036-50 | 50 mg | $1,216.00 |
* Prices listed are in USD. Taxes, shipping & handling not included. Contact us for bulk pricing.
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Overview
Wnt Inhibitor IWP-4 was identified in a high throughput screen for antagonists of the Wnt / β-catenin pathway. Wnt Inhibitor IWP-4 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, there by blocking Wnt secretion and activity. It also blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin 1 . New 50 mg size now available.