StemRNA Neuro

Wild-type human brain cell neurons for general purpose assays

Formerly called ReproNeuro.

Frozen human iPSC-derived neurons for 96-well high-throughput and high-content assays

• Frozen as a suspension of individualized neuroprogenitor cells
• Rapidly differentiate into neurons during in vitro growth and maturation
• Display measurable neuronal function
• Form dendritic connections leading to synchronized burst behavior around week 6 in vitro
• Responsive to various reference compounds that modulate neuron electrophysiology
• Expresses multiple neuron-specific markers, indicating a mixed population of neuron types
• Two different culture media are available separately

StemRNA Neuro iPS-derived neurons are cryopreserved using REPROCELL's proprietary cryopreservation technology. Thawed and plated StemRNA Neuro cells mature during 2-3 weeks of culture on surfaces treated with Neuro Coat (RCDN201).

Types of ReproNeuro Media

Note that one of the following media is required for proper maturation of the StemRNA Neuro cells:

• Neuro Culture Medium (RCDN101); standard medium for general purpose assays
• Neuro MQ Culture Medium (RCDN102); a specialty medium formulated with rat astrocyte supplementation, resulting in maximum performance in MEA (multi-electrode array) assays