StemRNA Sensory Neurons
REPROCELL

StemRNA Sensory Neurons

QTY Cat # Size Unit Price
RCDN004N 1 vial (1 million cells) $2,292.00

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Overview

iPSC-derived Sensory Neurons

Frozen human iPSC-derived neurons for high-throughput and high-content assays

Sensory neurons transmit pain signals generated by trauma, temperature, or chemicals to the central nervous system. Primary afferent nerves, evoked by non-nociceptive and nociceptive stimuli, reside in the dorsal root ganglion (DRG) of the spinal cord. REPROCELL has developed an alternative sensory neuron model using human-derived induced pluripotent stem cells (iPSC) to negate accessibility issues and improve ease of culture. These cells' expression of sensory markers was detected by immunocytochemistry. Multi-Electrode Array (MEA) analysis confirms these hiPSC-derived sensory neurons display the same functionality as primary DRG cells.

Requires Sensory Neuron Culture Medium (Cat. No. RDCN103)

StemRNA Sensory Neurons Respond to the irritant capsaicin. StemRNA Sensory Neurons show activation with increasing temperature, while iPSC-derived cortical neurons do not.