CI-hAELVi Immortalized Human Alveolar Epithelial Cells
| QTY | Cat # | Size | Unit Price |
|---|---|---|---|
|
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INS-CI-1015 | 1 vial (500K cells) | $9,430.00 |
* Prices listed are in USD. Taxes, shipping & handling not included. Contact us for bulk pricing.
Overview
Immortalized Human Alveolar Epithelial Cells
CI-hAELVi cells are immortalized human alveolar epithelial cells. Alveolar epithelial cells play a crucial role in the respiratory system by lining the alveoli, tiny air sacs within the lungs where gas exchange occurs. CI-hAELVis have been extensively used to model the air-blood barrier in vitro.
While the cells do show an AT-1 phenotype (expression of Caveolin, no surfactant secretion) in standard culture conditions, they adopt certain AT-2 characteristics in extended ALI culture conditions, including secretion of surfactants and formation of microvilli and lamellar structures.
There is a newer and improved alveolar cell line available, CI-huArlo, which is a direct derivative of CI-hAELVi.
This CI-hAELVi cell line is the result of a collaboration between HIPS, Saarbrücken (Germany), HZI, Braunschweig (Germany), and inscreenex.
Characteristics
- TEER of >1500 Ω/sqcm in Liquid-Liquid-Interface culture
- TEER of >2000Ω/sqcm in Air-Liquid-Interface culture
- Tight junctions (ZO1, Occludin)
- Susceptible to SARS-CoV-2 infection
Culture Conditions
- Culture Medium: huAEC Medium Kit for Alveolar Cells (Cat. No. INS-ME-1013)
- Culture Matrix: Coating Solution (Cat. No. INS-SU-1026-100ml)
- Cryopreservation Medium: Freezing Solution for Immortalized Cell Lines (Cat. No. INS-SU-1027)
Buying and Ordering the Cells
A license for Academic Researchers is also available. Please contact us for more information